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Euro Peerless Ferritin Turbi
Euro
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Brand | Euro |
Method | Ferritin Turbi |
R1 R2 R3 | 1 x 40 ml 1 x 10 ml 1 x 1 ml |
Product Description :
Recommended Use :Turbidimetric immunoassay for the quantitative determination of ferritin in human serum or plasma.
Principle of the method: Ferritin-turbilatex is a quantitative turbidimetric test for the measurement of ferritin in human serum or plasma. Latex particles coated with specific anti-human ferritin are agglutinated when mixed with samples containing ferritin. The agglutination causes an absorbance change, dependent upon the ferritin contents of the sample that can be quantified by comparison from a calibrator of known ferritin concentration.
Clinical Significance: Serum ferritin concentration usually reflects body iron stores and is considered one of the most reliable indicators of iron status of patients Whereas low serum concentrations of ferritin are always indicative of an iron deficiency, elevated concentrations can occur for variety of reasons. Thus, although elevated concentrations often indicate an excessive iron intake, they are also caused by liver disease, chronic inflammation and malignancies. Pregnant women, blood donors, hemodialysis patients. adolescents and children are groups particularly at risk.
Precaution: Components from human origin have been tested and found to be negative for the presence of HBsAg, HCV, and antibody to HIV (1/2). However handle cautiously as potentially infectious
Preparation: Ferritin Calibrator: Reconstitute (→) with 3.0 mL of distilled water. Mix gently and incubate at room temperature for about 10 minutes before testing.
Calibration:Use Ferritin Calibrator Reference07042. The sensitivity of the assay and the target value of the calibrator have been standardized against the 3rd International Standard of Ferritin (94/572,2008 WHO). Recalibrate when control results are out of specified values; when using a different lot of reagent and when the instrument is adjusted.
Calibration curve: Prepare the following dilutions of the FERR Calibrator using NaCl 9 g/L. To obtain the concentration of each dilution, multiply using the dilution factor
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